Back to Search
Start Over
Successful Management of Extensively Drug Resistant Pseudomonas aeruginosa -Infectious Scleritis after Pterygium Surgery.
- Source :
-
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Sep; Vol. 32 (7), pp. 1279-1283. Date of Electronic Publication: 2023 Jul 11. - Publication Year :
- 2024
-
Abstract
- Introduction and Purpose: We report a case of extensively drug-resistant (XDR) Pseudomonas aeruginosa (PA) scleritis after pterygium surgery.<br />Methods: Case report.<br />Results: A 58-year-old farmer presented with a 40-day history of severe pain, swelling, and blurred vision after a pterygium excision was performed at another institute. The patient was on multiple medications with no relief. The examination showed a nasally located scleral thinning in his right eye, with ulceration and infiltrates. Microbiology revealed Pseudomonas aeruginosa , which showed intermediate sensitivity to colistin only. The patient was administered topical (0.19%) and intravenous colistin and dexamethasone. There was a rapid reduction in symptoms, and the lesions healed over the next 2 months.<br />Conclusions: To the best of our knowledge, this is the first case report of XDR-PA scleritis. We suggest the possibility of evolving drug resistance caused by the iatrogenic use of antibiotics during the early stages of the disease course.
- Subjects :
- Humans
Middle Aged
Male
Glucocorticoids therapeutic use
Colistin therapeutic use
Ophthalmologic Surgical Procedures adverse effects
Drug Therapy, Combination
Dexamethasone therapeutic use
Dexamethasone administration & dosage
Microbial Sensitivity Tests
Scleritis microbiology
Scleritis drug therapy
Scleritis diagnosis
Scleritis etiology
Pterygium surgery
Pterygium drug therapy
Pseudomonas aeruginosa isolation & purification
Pseudomonas Infections diagnosis
Pseudomonas Infections drug therapy
Pseudomonas Infections microbiology
Pseudomonas Infections etiology
Eye Infections, Bacterial microbiology
Eye Infections, Bacterial diagnosis
Eye Infections, Bacterial drug therapy
Eye Infections, Bacterial etiology
Anti-Bacterial Agents therapeutic use
Drug Resistance, Multiple, Bacterial
Subjects
Details
- Language :
- English
- ISSN :
- 1744-5078
- Volume :
- 32
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Ocular immunology and inflammation
- Publication Type :
- Academic Journal
- Accession number :
- 37433154
- Full Text :
- https://doi.org/10.1080/09273948.2023.2232037