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Successful Management of Extensively Drug Resistant Pseudomonas aeruginosa -Infectious Scleritis after Pterygium Surgery.

Authors :
Dalal S
Murthy SI
Deogaokar K
Joseph J
Roy S
Source :
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Sep; Vol. 32 (7), pp. 1279-1283. Date of Electronic Publication: 2023 Jul 11.
Publication Year :
2024

Abstract

Introduction and Purpose: We report a case of extensively drug-resistant (XDR) Pseudomonas aeruginosa (PA) scleritis after pterygium surgery.<br />Methods: Case report.<br />Results: A 58-year-old farmer presented with a 40-day history of severe pain, swelling, and blurred vision after a pterygium excision was performed at another institute. The patient was on multiple medications with no relief. The examination showed a nasally located scleral thinning in his right eye, with ulceration and infiltrates. Microbiology revealed Pseudomonas aeruginosa , which showed intermediate sensitivity to colistin only. The patient was administered topical (0.19%) and intravenous colistin and dexamethasone. There was a rapid reduction in symptoms, and the lesions healed over the next 2 months.<br />Conclusions: To the best of our knowledge, this is the first case report of XDR-PA scleritis. We suggest the possibility of evolving drug resistance caused by the iatrogenic use of antibiotics during the early stages of the disease course.

Details

Language :
English
ISSN :
1744-5078
Volume :
32
Issue :
7
Database :
MEDLINE
Journal :
Ocular immunology and inflammation
Publication Type :
Academic Journal
Accession number :
37433154
Full Text :
https://doi.org/10.1080/09273948.2023.2232037