On the role of polyploid giant cells in oncogenesis and tumorigenesis.

Authors :: Niculescu VF
Source :: Medical oncology (Northwood, London, England) [Med Oncol] 2023 Jul 11; Vol. 40 (8), pp. 232. Date of Electronic Publication: 2023 Jul 11.
Publication Year :: 2023
Abstract: This correspondence is in response to the commentary by Jinsong Liu ( https://doi.org/10.1007/s12032-023-02038-1 ) to my article "The evolutionary cancer gene network theory versus embryogenic hypotheses" published in Medical Oncology (40:114, 2023). Liu's commentary engages head-on with the evolutionary cancer genome theory and defends his more histopathologically-embryogenically oriented theory of 2020. The dispute revolves, among other things, around the role of polyploid giant MGRS/PGCCs structures in oncogenesis and tumorigenesis.<br /> (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)