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The Role of Personalized Medicine in Companion Animal Cardiology.

Authors :
Rivas VN
Stern JA
Ueda Y
Source :
The Veterinary clinics of North America. Small animal practice [Vet Clin North Am Small Anim Pract] 2023 Nov; Vol. 53 (6), pp. 1255-1276. Date of Electronic Publication: 2023 Jul 07.
Publication Year :
2023

Abstract

Cardiomyopathies remain one of the most common inherited cardiac diseases in both human and veterinary patients. To date, well over 100 mutated genes are known to cause cardiomyopathies in humans with only a handful known in cats and dogs. This review highlights the need and use of personalized one-health approaches to cardiovascular case management and advancement in pharmacogenetic-based therapy in veterinary medicine. Personalized medicine holds promise in understanding the molecular basis of disease and ultimately will unlock the next generation of targeted novel pharmaceuticals and aid in the reversal of detrimental effects at a molecular level.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1878-1306
Volume :
53
Issue :
6
Database :
MEDLINE
Journal :
The Veterinary clinics of North America. Small animal practice
Publication Type :
Academic Journal
Accession number :
37423841
Full Text :
https://doi.org/10.1016/j.cvsm.2023.05.016