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Clinical outcomes in women with endometrial polyps underwent conservative management.
- Source :
-
Taiwanese journal of obstetrics & gynecology [Taiwan J Obstet Gynecol] 2023 Jul; Vol. 62 (4), pp. 553-558. - Publication Year :
- 2023
-
Abstract
- Objective: To evaluate the regression rate of endometrial polyps (EPs) in a cohort of asymmetric women after conservative follow-up.<br />Materials and Methods: In this retrospective cohort study, a total of 1006 women with asymptomatic EPs were treated with expectant management or hormonal drugs between June 1999 and May 2018. Four hundred forty-eight women (44.5%) were administered with hormonal medications and 558 women were managed expectantly (55.5%). Office hysteroscopy was performed to confirm the diagnosis and regression of EPs. Hormonal administration included oral contraceptives, progestin and cyclic estrogen/progestin regimen according to physicians' preferences. Clinical characteristics, including the patient's age, body mass index, parity, and type of conservative management were collected.<br />Results: The mean observation time was 14.1 ± 18.5 months (range, 1-162 months). The overall regression rate of EPs in this cohort was 33.5%, 24.6% occurred after medication and 8.9% after expectant management. Patient age (<50 years) (p < 0.001), follow-up period (p = 0.005) and hormonal drugs used (p < 0.001) were significantly associated with EP regression. Twenty-four (7.1%) of the 337 EP regression patients later developed recurrent disease. Follow-up period (p < 0.001) and hormonal drugs used (p = 0.032) were closely related to polyp recurrence after initial regression. Nevertheless, multivariate logistic regression analysis revealed that hormonal drugs used was significantly associated with the regression (p < 0.001) and recurrence (p = 0.016) of EPs.<br />Conclusion: Women aged 50 or less are more suitable for conservative treatment for EPs. Hormonal drugs used could increase the incidence of EP regression.<br />Competing Interests: Declaration of competing interest The authors have no conflicts of interest relevant to this article.<br /> (Copyright © 2023. Published by Elsevier B.V.)
Details
- Language :
- English
- ISSN :
- 1875-6263
- Volume :
- 62
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Taiwanese journal of obstetrics & gynecology
- Publication Type :
- Academic Journal
- Accession number :
- 37407193
- Full Text :
- https://doi.org/10.1016/j.tjog.2022.08.022