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Chimeric Antigen Receptor T-Cell Therapy in Aggressive B-Cell Lymphoma.
- Source :
-
Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2023 Dec; Vol. 37 (6), pp. 1053-1075. Date of Electronic Publication: 2023 Jun 20. - Publication Year :
- 2023
-
Abstract
- Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary therapy increasingly used in the treatment of non-Hodgkin B-cell lymphoma. This review focuses on the use of CAR T-cell therapy in aggressive B-cell lymphoma including clinical indications, known short- and long-term toxicity, mechanisms of CAR T-cell efficacy and tumor resistance, and future directions in the treatment of aggressive lymphoma with CAR T-cell therapy.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1558-1977
- Volume :
- 37
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Hematology/oncology clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 37349153
- Full Text :
- https://doi.org/10.1016/j.hoc.2023.05.007