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Prevention of the Genotoxic Effects of Doxorubicin with Anthocyanin-Containing Complex from Sorbus aucuparia L. Fruit.
- Source :
-
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2023 May; Vol. 175 (1), pp. 49-53. Date of Electronic Publication: 2023 Jun 20. - Publication Year :
- 2023
-
Abstract
- We studied the effect of an anthocyanin-containing complex from the fruits of S. aucuparia L. on doxorubicin-induced genotoxicity in bone marrow cells of C57BL/6 mice. The complex reduced the genotoxic effect doxorubicin in metaphase plates of bone marrow cells in 24, 48 h, and 10 days after the administration of the cytostatic. The mean number of single fragments and the fraction of cells with gaps and aberrant metaphases also decreased.<br /> (© 2023. Springer Science+Business Media, LLC, part of Springer Nature.)
Details
- Language :
- English
- ISSN :
- 1573-8221
- Volume :
- 175
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Bulletin of experimental biology and medicine
- Publication Type :
- Academic Journal
- Accession number :
- 37338761
- Full Text :
- https://doi.org/10.1007/s10517-023-05809-y