Back to Search
Start Over
An AIE active fluorescence sensor for measuring Fe 3+ in aqueous media and an iron deficiency anemia drug.
- Source :
-
Organic & biomolecular chemistry [Org Biomol Chem] 2023 Jul 05; Vol. 21 (26), pp. 5406-5412. Date of Electronic Publication: 2023 Jul 05. - Publication Year :
- 2023
-
Abstract
- In this study, a new tetraphenylethene derivative bearing triazole and pyridine moieties (TPE-TAP) was synthesized using click chemistry. The fluorescence sensing properties of TPE-TAP were investigated in almost 100% aqueous media. For this purpose, first of all, structural characterization of the newly synthesized compound TPE-TAP was performed by NMR and HRMS analyses. Then, the optical behavior of TPE-TAP was investigated in different ratios of a THF-water mixture (0-98%). The obtained results showed that the best fluorescence for TPE-TAP was observed in the presence of 98% water in the medium. Then, the ion selectivity of TPE-TAP was determined using 19 different cations in the THF-water medium (2 : 98 v/v%). It was observed that among the cations studied, only Fe <superscript>3+</superscript> quenched the fluorescence of TPE-TAP. The detection limit and binding constant values of TPE-TAP for Fe <superscript>3+</superscript> were calculated as 1.3 μM and 26.65 M <superscript>-2</superscript> , respectively, from the graph results of the decrease in the fluorescence intensity of TPE-TAP in the presence of Fe <superscript>3+</superscript> at different concentrations. In addition, the study investigating the selectivity of TPE-TAP in the presence of 18 cations other than Fe <superscript>3+</superscript> showed that none of the studied cations interfered with Fe <superscript>3+</superscript> . Practical application of TPE-TAP was also carried out using a commercial iron drug. All results showed that TPE-TAP is a fluorometric sensor highly selective, sensitive, and suitable for practical application for Fe <superscript>3+</superscript> ions in aqueous medium.
Details
- Language :
- English
- ISSN :
- 1477-0539
- Volume :
- 21
- Issue :
- 26
- Database :
- MEDLINE
- Journal :
- Organic & biomolecular chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 37334520
- Full Text :
- https://doi.org/10.1039/d3ob00602f