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Highly responsive and sensitive non-enzymatic electrochemical sensor for the detection of β-NADH in food, environmental and biological samples using AuNP on polydopamine/titanium carbide composite.

Authors :
Prasanna SB
Bahajjaj AAA
Lee YH
Lin YC
Dhawan U
Sakthivel R
Chung RJ
Source :
Food chemistry [Food Chem] 2023 Nov 15; Vol. 426, pp. 136609. Date of Electronic Publication: 2023 Jun 12.
Publication Year :
2023

Abstract

In this study, a polydopamine/titanium carbide adorned with gold nanoparticles (Au@PDA/TiC) composite was prepared by a simple stirring technique and it was used for the dual-technique detection of β-Nicotinamide adenine dinucleotide (NADH). The Au@PDA/TiC-modified glassy carbon electrode (GCE) oxidized NADH at a very low oxidation potential of approximately 0.60 V vs Ag/AgCl in pH = 7.0 (0.1 M PBS) via the transfer of two electrons and one proton (from NADH to NAD <superscript>+</superscript> ). Based on the (i-t) amperometry mode, NADH can be quantified with a linear range of 0.018-674 μM and LOD of 0.0062 µM. In addition to the DPV mode, the electrochemical sensor had a linearity of 5-450 µM with a LOD of 3.17 µM. The developed sensor exhibited remarkable analytical performances concerning high sensitivity, electrocatalytic activity, low detection limit, wide linearity, appreciable specificity, repeatability, stability, reproducibility, and adequate recovery results in food, environmental and biological samples.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1873-7072
Volume :
426
Database :
MEDLINE
Journal :
Food chemistry
Publication Type :
Academic Journal
Accession number :
37331138
Full Text :
https://doi.org/10.1016/j.foodchem.2023.136609