Residual excessive daytime sleepiness in patients with sleep apnea syndrome receiving continuous positive airway pressure in Japan: A single-center study.

Excessive daytime sleepiness (EDS) is a symptom of sleep apnea syndrome (SAS). In some patients with SAS who undergo continuous positive airway pressure (CPAP) therapy, EDS persists (residual EDS). However, knowledge of residual EDS in Japan is limited. Therefore, we examined EDS as defined by the Japanese version of the Epworth Sleepiness Scale (a score of ≥11) before and after long-term (≥1 year) CPAP therapy in 490 patients with SAS. Good adherence to CPAP therapy was defined as its use for at least 4 h during 70% of the nights. The prevalence of residual EDS was 9.4%. Residual EDS was negatively associated with good adherence to CPAP therapy. Furthermore, the longer the CPAP therapy duration after initiation, the lower the prevalence of residual EDS. Therefore, the findings on the prevalence of residual EDS and its association with CPAP therapy in Japan are probably similar to those of other countries.
Competing Interests: Conflict of interest Satoshi Hamada received research grants from Teijin Pharma outside the submitted work; Susumu Sato received research grants from Philips Japan, ResMed Japan, Fukuda Denshi, Fukuda Lifetec Keiji, Fuji Film Corporation, and Nippon Boehringer Ingelheim, outside the submitted work; Jumpei Togawa, Hironobu Sunadome, Tadao Nagasaki, and Naomi Takahashi received research grants from Philips Japan, ResMed Japan, Fukuda Denshi, and Fukuda Lifetec Keiji, outside the submitted work; Toyohiro Hirai has no conflict of interest.
(Copyright © 2023 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.)