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Onset model of mutually catalytic self-replicative systems formed by an assembly of polynucleotides.
- Source :
-
Physical review. E [Phys Rev E] 2023 May; Vol. 107 (5-1), pp. 054404. - Publication Year :
- 2023
-
Abstract
- Self-replicability is a unique attribute observed in all living organisms, and the question of how the life was physically initiated could be equivalent to the question of how self-replicating informative polymers were formed in the abiotic material world. It has been suggested that the present DNA and proteins world was preceded by an RNA world in which genetic information of RNA molecules was replicated by the mutual catalytic function of RNA molecules. However, the important question of how the transition occurred from a material world to the very early pre-RNA world remains unsolved both experimentally and theoretically. We present an onset model of mutually catalytic self-replicative systems formed in an assembly of polynucleotides. A quantitative expression of the critical condition for the onset of growing fluctuation towards self-replication in this model is obtained by analytical and numerical calculations.
- Subjects :
- DNA genetics
Polynucleotides genetics
RNA genetics
Subjects
Details
- Language :
- English
- ISSN :
- 2470-0053
- Volume :
- 107
- Issue :
- 5-1
- Database :
- MEDLINE
- Journal :
- Physical review. E
- Publication Type :
- Academic Journal
- Accession number :
- 37329042
- Full Text :
- https://doi.org/10.1103/PhysRevE.107.054404