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Recent advances in cellulose, pectin, carrageenan and alginate-based oral drug delivery systems.

Authors :
Raghav N
Vashisth C
Mor N
Arya P
Sharma MR
Kaur R
Bhatti SP
Kennedy JF
Source :
International journal of biological macromolecules [Int J Biol Macromol] 2023 Jul 31; Vol. 244, pp. 125357. Date of Electronic Publication: 2023 Jun 14.
Publication Year :
2023

Abstract

Polymers-based drug delivery systems constitute one of the highly explored thrust areas in the field of the medicinal and pharmaceutical industries. In the past years, the properties of polymers have been modified in context to their solubility, release kinetics, targeted action site, absorption, and therapeutic efficacy. Despite the availability of diverse synthetic polymers for the bioavailability enhancement of drugs, the use of natural polymers is still highly recommended due to their easy availability, accessibility, and non-toxicity. The aim of the review is to provide the available literature of the last five years on oral drug delivery systems based on four natural polymers i.e., cellulose, pectin, carrageenan, and alginate in a concise and tabulated manner. In this review, most of the information is in tabulated form to provide easy accessibility to the reader. The data related to active pharmaceutical ingredients and supported components in different formulations of the mentioned polymers have been made available.<br />Competing Interests: Declaration of competing interest Authors declare no conflict of interest.<br /> (Copyright © 2023 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1879-0003
Volume :
244
Database :
MEDLINE
Journal :
International journal of biological macromolecules
Publication Type :
Academic Journal
Accession number :
37327920
Full Text :
https://doi.org/10.1016/j.ijbiomac.2023.125357