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Decoding evolutionary trajectories of ovarian cancer metastasis.
- Source :
-
Cancer cell [Cancer Cell] 2023 Jun 12; Vol. 41 (6), pp. 1008-1010. - Publication Year :
- 2023
-
Abstract
- The genetic changes during high-grade serous ovarian cancer metastasis have largely remained a mystery. Lahtinen et al. show that ovarian cancer metastasizes along three different evolutionary states that have distinct mutations and signaling pathways, potentially allowing the identification of targeted treatments.<br />Competing Interests: Declaration of interests E.L. receives funds for his laboratory research from Abbvie and Arsenal bioscience.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Female
Mutation
Ovarian Neoplasms genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3686
- Volume :
- 41
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Cancer cell
- Publication Type :
- Academic Journal
- Accession number :
- 37311411
- Full Text :
- https://doi.org/10.1016/j.ccell.2023.05.011