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Prognosis to Radiation Unlocked: How Hypoxia Methylome May Hold the Key in HNSCC.
- Source :
-
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Aug 15; Vol. 29 (16), pp. 2954-2956. - Publication Year :
- 2023
-
Abstract
- Hypoxia in head and neck tumors has proven to be predictive of outcomes. Current hypoxia signatures have failed for patient treatment selection. In a recent study, the authors identified a hypoxia methylation signature as a more robust biomarker in head and neck squamous cell carcinoma and shed light into the mechanism of hypoxia-mediated treatment resistance. See related article by Tawk et al., p. 3051.<br /> (©2023 American Association for Cancer Research.)
- Subjects :
- Humans
Squamous Cell Carcinoma of Head and Neck genetics
Squamous Cell Carcinoma of Head and Neck radiotherapy
Tumor Hypoxia genetics
Epigenome
Neoplasm Recurrence, Local
Prognosis
Hypoxia genetics
Chemoradiotherapy
DNA
Carcinoma, Squamous Cell genetics
Carcinoma, Squamous Cell radiotherapy
Carcinoma, Squamous Cell pathology
Papillomavirus Infections
Head and Neck Neoplasms genetics
Head and Neck Neoplasms radiotherapy
Subjects
Details
- Language :
- English
- ISSN :
- 1557-3265
- Volume :
- 29
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Publication Type :
- Academic Journal
- Accession number :
- 37310809
- Full Text :
- https://doi.org/10.1158/1078-0432.CCR-23-1132