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Prognosis to Radiation Unlocked: How Hypoxia Methylome May Hold the Key in HNSCC.

Authors :
Heft Neal ME
Brenner JC
Source :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Aug 15; Vol. 29 (16), pp. 2954-2956.
Publication Year :
2023

Abstract

Hypoxia in head and neck tumors has proven to be predictive of outcomes. Current hypoxia signatures have failed for patient treatment selection. In a recent study, the authors identified a hypoxia methylation signature as a more robust biomarker in head and neck squamous cell carcinoma and shed light into the mechanism of hypoxia-mediated treatment resistance. See related article by Tawk et al., p. 3051.<br /> (©2023 American Association for Cancer Research.)

Details

Language :
English
ISSN :
1557-3265
Volume :
29
Issue :
16
Database :
MEDLINE
Journal :
Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Type :
Academic Journal
Accession number :
37310809
Full Text :
https://doi.org/10.1158/1078-0432.CCR-23-1132