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[Co-occurrence of Whipple's disease and hyperparathyroidism - coincidence or causal relationship?]

Authors :
Weber M
Dancygier H
Blasberg T
Wedi E
Source :
Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2023 Sep; Vol. 61 (9), pp. 1214-1220. Date of Electronic Publication: 2023 Jan 10.
Publication Year :
2023

Abstract

Whipple's disease is a rare infectious disease with multiple clinical manifestations. The disease is named after George Hoyt Whipple, who first recorded the illness in 1907 after conducting the autopsy of a 36-year-old man with weight loss, diarrhea, and arthritis. Under the microscope, Whipple discovered a rod-shaped bacterium in the patient's intestinal wall, which was not confirmed as a new bacterial species until 1992, when it was named Tropheryma whipplei.Recurrence of Whipple's disease can occur years after an initial diagnosis and often manifests with extraintestinal symptoms such as arthritides or skin efflorescences, years before a gastrointestinal complaint. However, the simultaneous occurrence of primary hyperparathyroidism in the present case is a hitherto unknown clinical picture and opens up new questions and perspectives in the context of diagnostics and therapy.<br />Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.<br /> (Thieme. All rights reserved.)

Details

Language :
German
ISSN :
1439-7803
Volume :
61
Issue :
9
Database :
MEDLINE
Journal :
Zeitschrift fur Gastroenterologie
Publication Type :
Academic Journal
Accession number :
37309099
Full Text :
https://doi.org/10.1055/a-1984-0403