Bone marrow metastasis of testicular germ cell tumour: A rare case.

Authors :: Dubey H
Jain G
Kumar C
Ranjan A
Batra A
Chellapuram SK
Gupta S
Goel H
Sharma A
Tanwar P
Source :: Heliyon [Heliyon] 2023 May 29; Vol. 9 (6), pp. e16703. Date of Electronic Publication: 2023 May 29 (Print Publication: 2023).
Publication Year :: 2023
Abstract: Germ cell tumour (GCT) is the most common testicular tumour that commonly presents as a painless mass. Bone marrow metastasis in cases of testicular GCT is rare; only few case reports are available till date in the literature. Here an adult male presented with an intra-abdominal mass in right iliac fossa with inguinal lymphadenopathy with a deranged kidney function test. Bone marrow (BM) aspirate smear revealed metastatic tumour cells, but BM-biopsy was unremarkable. High serum Beta - HCG (38286 mIU/L) pointed towards germ cell lesion. Lymph node biopsy along with immunomarkers confirmed metastatic foci from germ cell tumor and managed as per standard protocol. Rarely BM aspirate is seen positive for malignancy, while biopsy turns out to be negative. Secondly, BM metastasis of GCT should be considered while dealing with cases like this.<br />Informed Consent: This is certified that the informed consent has been obtained from the patient.<br />Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper<br /> (© 2023 Published by Elsevier Ltd.)