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Radioembolization Planning With Dual-Isotope Acquisition of 166 Ho-Labeled Microparticles and 99m Tc-Mebrofenin.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2023 Aug 01; Vol. 48 (8), pp. 719-721. Date of Electronic Publication: 2023 Jun 08. - Publication Year :
- 2023
-
Abstract
- Abstract: A 76-year-old man with hepatocellular carcinoma was referred for liver radioembolization. Given a prior left hemihepatectomy, it was clinically important to consider potentially irradiated healthy liver at planning. Thus, at the SPECT/CT imaging of the scout dose 166 Ho-microparticles before injected superselectively in the right hepatic artery, 99m Tc-mebrofenin was injected intravenously, and functional volumetry SPECT was performed simultaneously. Based on the 2 image sets, the nonirradiated healthy liver was calculated as 1589 mL (functional liver reserve of 85.5% on 99m Tc-mebrofenin SPECT). Posttreatment dosimetry calculations showed optimal normal tissue and tumor absorbed doses, and the patient is clinically well after 3 months.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
- Subjects :
- Male
Humans
Aged
Tomography, Emission-Computed, Single-Photon methods
Yttrium Radioisotopes therapeutic use
Isotopes
Liver Neoplasms diagnostic imaging
Liver Neoplasms radiotherapy
Liver Neoplasms drug therapy
Carcinoma, Hepatocellular diagnostic imaging
Carcinoma, Hepatocellular radiotherapy
Carcinoma, Hepatocellular drug therapy
Embolization, Therapeutic
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 48
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 37290424
- Full Text :
- https://doi.org/10.1097/RLU.0000000000004732