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Neuroendocrine Tumor of the Ampulla of Vater: A Case Report.
- Source :
-
Cureus [Cureus] 2023 May 05; Vol. 15 (5), pp. e38588. Date of Electronic Publication: 2023 May 05 (Print Publication: 2023). - Publication Year :
- 2023
-
Abstract
- Neuroendocrine tumors (NETs) of the ampulla of Vater are extremely rare. Here, we discuss the clinical presentation, diagnostic challenges, and treatment options of a recently experienced case of NET of the ampulla of Vater in light of the literature. A 56-year-old woman presented with recurrent upper abdominal pain. Ultrasonography (USG) of the whole abdomen showed multiple gallstones along with a dilated common bile duct (CBD). For evaluating the dilated CBD, a magnetic resonance cholangiopancreatography was performed, which revealed the double-duct sign. Subsequently, an upper gastrointestinal endoscopy showed a bulged-out ampulla of the Vater. Biopsy and histopathological examination of the growth yielded the diagnosis of adenocarcinoma. A Whipple procedure was performed. Macroscopically, a 2 cm growth was noted involving the ampulla of Vater, and microscopic findings were consistent with a well-differentiated NET, grade 1 (low grade). The diagnosis was further confirmed by immunohistochemical staining (pan-cytokeratin positive, synaptophysin positive, and focally chromogranin positive). Her postoperative course was uneventful except for delayed gastric emptying. A detailed evaluation and a high index of suspicion are required for the diagnosis of this rare tumor. Treatment is relatively easier after a proper diagnosis.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2023, Aman et al.)
Details
- Language :
- English
- ISSN :
- 2168-8184
- Volume :
- 15
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cureus
- Publication Type :
- Report
- Accession number :
- 37284411
- Full Text :
- https://doi.org/10.7759/cureus.38588