Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword.

Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after severe COVID-19 infection and developed cryptococcal meningitis. Opportunistic infection may arise from the use of immunomodulation in severe COVID-19, especially in the elderly population. This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment.
Competing Interests: No Conflict of Interest is declared
(Copyright (c) 2023 Hilal W Abdessamad, Michel Achkar, Amal Al Zoghbi, Mohamad Fleifel, Abdul Rahman Ousta, Ahmad Kassar, Nadia L Samaha, Rita Nemr, Anna Farra, Jacques E Mokhbat, Rola Husni.)