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Case of elderly onset possible neuro-Behçet's disease with HLA-B51 homozygosity.

Authors :
Shiraishi W
Tsujimoto Y
Matsuyoshi A
Hashimoto T
Source :
BMJ case reports [BMJ Case Rep] 2023 Jun 01; Vol. 16 (6). Date of Electronic Publication: 2023 Jun 01.
Publication Year :
2023

Abstract

Behçet's disease commonly affects 20-40-year-old men and shows ophthalmo-dermatological manifestations. Here, we report a man in his 70s with acute onset of dysarthria, dysphagia and hemiplegia showing brainstem and subcortical lesions, which responded to steroid and colchicine therapy. He had a history of uveitis and was homozygous for the human leucocyte antigen-B51 allele, and we clinically diagnosed him with acute neuro-Behçet's disease. Old-age onset neuro-Behçet's disease is uncommon, and as far as we know, this is the oldest case of the first attack of neuro-Behçet's disease. Clinicians should consider Behçet's disease even for elderly patients.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Details

Language :
English
ISSN :
1757-790X
Volume :
16
Issue :
6
Database :
MEDLINE
Journal :
BMJ case reports
Publication Type :
Academic Journal
Accession number :
37263675
Full Text :
https://doi.org/10.1136/bcr-2022-252033