Response to Comment on "Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice".

Authors :: Albornoz EA
Gordon R
Kumar V
Robertson AAB
Schroder K
Woodruff TM
Source :: Science translational medicine [Sci Transl Med] 2023 May 17; Vol. 15 (696), pp. eadh0604. Date of Electronic Publication: 2023 May 17.
Publication Year :: 2023
Abstract: We have replicated our original finding of elevated cleaved caspase-1 in mouse brains and neuroprotection by an NLRP3 inflammasome inhibitor in two mouse models of Parkinson's disease.

Subjects :: Mice
Animals
alpha-Synuclein
NLR Family, Pyrin Domain-Containing 3 Protein
Dopamine
Inflammasomes
Parkinson Disease pathology

Full Text Access

Tools