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Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022.

Authors :
Linkevicius M
Bonnin RA
Alm E
Svartström O
Apfalter P
Hartl R
Hasman H
Roer L
Räisänen K
Dortet L
Pfennigwerth N
Hans JB
Tóth Á
Buzgó L
Cormican M
Delappe N
Monaco M
Giufrè M
Hendrickx AP
Samuelsen Ø
Pöntinen AK
Caniça M
Manageiro V
Oteo-Iglesias J
Pérez-Vázquez M
Westmo K
Mäkitalo B
Palm D
Monnet DL
Kohlenberg A
Source :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2023 May; Vol. 28 (19).
Publication Year :
2023

Abstract

Whole genome sequencing data of 874 Escherichia coli isolates carrying bla <subscript>NDM-5</subscript> from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidrug-resistant. Further spread of E. coli carrying bla <subscript>NDM-5</subscript> would leave limited treatment options for serious E. coli infections.

Details

Language :
English
ISSN :
1560-7917
Volume :
28
Issue :
19
Database :
MEDLINE
Journal :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Publication Type :
Academic Journal
Accession number :
37166762
Full Text :
https://doi.org/10.2807/1560-7917.ES.2023.28.19.2300209