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Successful Treatment with Steroids in a Patient with Vanishing Bile Duct Syndrome and Acute Tubular Necrosis.
- Source :
-
Internal medicine (Tokyo, Japan) [Intern Med] 2024 Jan 01; Vol. 63 (1), pp. 57-61. Date of Electronic Publication: 2023 May 10. - Publication Year :
- 2024
-
Abstract
- Vanishing bile duct syndrome (VBDS) is a rare but potentially serious cholestatic liver disease caused by various etiologies, including drugs. We herein report a complicated case of VBDS with acute tubular necrosis (ATN) that improved significantly with steroid treatment. An Asian man in his 30s was admitted with the acute onset of severe jaundice and a decline in the renal function. Although initial treatment with ursodeoxycholic acid did not reduce jaundice or renal dysfunction, steroid treatment remarkably improved the VBDS and ATN to within the respective normal ranges. Steroid treatment can be considered in cases of VBDS that appear to have an immune-mediated cause.
Details
- Language :
- English
- ISSN :
- 1349-7235
- Volume :
- 63
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Internal medicine (Tokyo, Japan)
- Publication Type :
- Academic Journal
- Accession number :
- 37164665
- Full Text :
- https://doi.org/10.2169/internalmedicine.1826-23