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Scale-free dynamics in the core-periphery topography and task alignment decline from conscious to unconscious states.
- Source :
-
Communications biology [Commun Biol] 2023 May 09; Vol. 6 (1), pp. 499. Date of Electronic Publication: 2023 May 09. - Publication Year :
- 2023
-
Abstract
- Scale-free physiological processes are ubiquitous in the human organism. Resting-state functional MRI studies observed the loss of scale-free dynamics under anesthesia. In contrast, the modulation of scale-free dynamics during task-related activity remains an open question. We investigate scale-free dynamics in the cerebral cortex's unimodal periphery and transmodal core topography in rest and task states during three conscious levels (awake, sedation, and anesthesia) complemented by computational modelling (Stuart-Landau model). The empirical findings demonstrate that the loss of the brain's intrinsic scale-free dynamics in the core-periphery topography during anesthesia, where pink noise transforms into white noise, disrupts the brain's neuronal alignment with the task's temporal structure. The computational model shows that the stimuli's scale-free dynamics, namely pink noise distinguishes from brown and white noise, also modulate task-related activity. Together, we provide evidence for two mechanisms of consciousness, temporo-spatial nestedness and alignment, suggested by the Temporo-Spatial Theory of Consciousness (TTC).<br /> (© 2023. The Author(s).)
- Subjects :
- Humans
Unconsciousness
Computer Simulation
Rest
Consciousness
Anesthesia
Subjects
Details
- Language :
- English
- ISSN :
- 2399-3642
- Volume :
- 6
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Communications biology
- Publication Type :
- Academic Journal
- Accession number :
- 37161021
- Full Text :
- https://doi.org/10.1038/s42003-023-04879-y