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Neurotransmitters arrive to control systemic autoimmunity.
- Source :
-
Cell metabolism [Cell Metab] 2023 May 02; Vol. 35 (5), pp. 728-729. - Publication Year :
- 2023
-
Abstract
- Immune cell microenvironment plays a major role in the aberrant function of immune cells in systemic lupus erythematosus. Zeng and co-authors show that in human and murine lupus, splenic stromal cell-derived acetylcholine switches B cell metabolism to fatty acid oxidation and promotes B cell autoreactivity and disease development.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1932-7420
- Volume :
- 35
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cell metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 37137285
- Full Text :
- https://doi.org/10.1016/j.cmet.2023.04.004