The Effectiveness of Biotin (Vitamin B 7 ) Added to the Diet in Improving the Efficiency of Productivity, and Some Physiological Traits for Broiler Chickens (Ross-308) Exposed to Oxidative Stress.

Biotin (B ₇ ) acts as an antioxidant, as it inhibits the effect of many free radicals that are naturally formed within the organism's body. This study aimed to determine the effect of adding different concentrations of biotin to the diet of broilers exposed to oxidative stress in improving productive and physiological performance. 180 unsexed Ross-308 one-day age chicks of broiler chickens were used, and they were reared together until 7 days. Then the chicks were randomly distributed into 5 treatments; each treatment included 3 replicates, 12 chicks for each replicate. Oxidative stress was induced by adding 0.5% H ₂ O ₂ to drinking water. The first treatment, T1 (control), was free from adding B ₇ or H ₂ O ₂ , and the second treatment (T2): was a positive control treatment free from adding vitamin B ₇ + water added to it H ₂ O ₂ at an average of 0.5%. The third treatment (T3): adding 550 micrograms of B ₇ /kg of feed + water added H ₂ O ₂ at an average of 0.5%. Fourth treatment (T4): 650 micrograms/kg vitamin B ₇ + water with 0.5% H ₂ O ₂ added on average. Fifth treatment (T5): 750 micrograms of vitamin B ₇ /kg of feed + 0.5% H ₂ O ₂ added to the water. The results of adding vitamin B ₇ to the diet of T4 and T5 birds exposed to oxidative stress showed a significant increase ( P <0.05) in the average live body weight, total weight gain and cumulative feed consumption average, and the best cumulative feed conversion ratio for treated birds (T3, T4, T5). In comparison to the other therapies, all additional vitamin B ₇ treatments demonstrated a significant decrease ( P <0.05) in the concentrations of glucose, cholesterol, triglycerides, as well as Malondialdehyde (MDA), and low-density lipoproteins (LDL) and a significant increase ( P <0.05) in the concentrations of high-density lipoproteins (HDL) and total protein. The concentration of glutathione peroxidase (GSH-Px) was significantly elevated ( P <0.05) in the serum of T5-treated birds compared to all other treatments. We conclude that adding vitamin B ₇ in different concentrations improved the productivity and some physiological traits of broilers exposed to the induced oxidative stress compared with the negative and positive control treatments.
Competing Interests: The authors declare that they have no conflict of interest.