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Slowly Progressive Bone Marrow Metastasis of Gastric Cancer Followed-up Without Treatment.
- Source :
-
In vivo (Athens, Greece) [In Vivo] 2023 May-Jun; Vol. 37 (3), pp. 1389-1393. - Publication Year :
- 2023
-
Abstract
- Background/aim: Bone marrow metastasis (BMM) of gastric cancer (GC) is complicated by disseminated intravascular coagulation syndrome (DIC), which is more prominent in poorly differentiated carcinoma. This is one of the first case reports of a slowly progressing BMM of GC after approximately 1 year of follow-up without treatment.<br />Case Report: A 72-year-old woman underwent total gastrectomy and splenectomy for GC in February 2012. The pathological diagnosis was that of a moderately differentiated adenocarcinoma. Five years later in December 2017, she developed anemia; however, its cause remained unknown. Due to worsening of the anemia, the patient visited the Kakogawa Central City Hospital in October 2018. Bone marrow biopsy revealed an infiltration of caudal type homeobox 2-positive cancer cells, and our diagnosis was BMM of GC. There was no DIC. The incidence of BMM is high in well- or moderately differentiated breast cancer but rarely causes DIC.<br />Conclusion: As with breast cancer, in moderately differentiated cancer cells, BMM of GC may progress slowly after the appearance of symptoms without causing DIC.<br /> (Copyright © 2023, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
- Subjects :
- Female
Humans
Aged
Bone Marrow pathology
Antineoplastic Combined Chemotherapy Protocols adverse effects
Stomach Neoplasms pathology
Bone Marrow Neoplasms drug therapy
Bone Marrow Neoplasms secondary
Disseminated Intravascular Coagulation complications
Disseminated Intravascular Coagulation drug therapy
Bone Neoplasms secondary
Breast Neoplasms complications
Subjects
Details
- Language :
- English
- ISSN :
- 1791-7549
- Volume :
- 37
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- In vivo (Athens, Greece)
- Publication Type :
- Academic Journal
- Accession number :
- 37103098
- Full Text :
- https://doi.org/10.21873/invivo.13222