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A case of idiopathic multicentric Castleman disease with pulmonary hyalinizing granuloma-like multiple pulmonary nodules.

Authors :
Hatano H
Tsujimoto Y
Watanabe H
Tsukada A
Izumi S
Nagasaka S
Igari T
Suzuki M
Iikura M
Hojo M
Source :
Respiratory investigation [Respir Investig] 2023 Jul; Vol. 61 (4), pp. 405-408. Date of Electronic Publication: 2023 Apr 24.
Publication Year :
2023

Abstract

A 41-year-old man presented with chronic cough and chest pain. Laboratory tests revealed anemia, inflammation, hypoalbuminemia, polyclonal hypergammaglobulinemia, and elevated interleukin-6 levels. Computed tomography revealed diffuse bilateral pulmonary nodules and multicentric lymphadenopathy. Histopathology of the pulmonary nodule resembled pulmonary hyalinizing granuloma (PHG), whereas lymph node histopathology was consistent with idiopathic multicentric Castleman disease (iMCD). The patient was diagnosed with iMCD involving PHG-like pulmonary nodules. Little is known about the association between these two diseases, and the present case provides insights regarding the relationship between PHG and iMCD.<br />Competing Interests: Conflict of Interest The authors declare no conflicts of interest.<br /> (Copyright © 2023 [The Author/The Authors]. Published by Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
2212-5353
Volume :
61
Issue :
4
Database :
MEDLINE
Journal :
Respiratory investigation
Publication Type :
Report
Accession number :
37099891
Full Text :
https://doi.org/10.1016/j.resinv.2023.03.003