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Heart Failure with Preserved vs. Reduced Ejection Fraction: Patient Characteristics, In-hospital Treatment and Mortality-DanAHF, a Nationwide Prospective Study.
- Source :
-
Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2024 Apr; Vol. 17 (2), pp. 265-274. Date of Electronic Publication: 2023 Apr 13. - Publication Year :
- 2024
-
Abstract
- This study aims to describe baseline characteristics and in-hospital management of a patient cohort hospitalized with acute heart failure (AHF). Adult patients in Denmark admitted with a medical diagnosis during a 7-day period were reviewed for symptoms and clinical findings suggestive of AHF. HFpEF was defined as LVEF ≥ 45%. Of 5194 patients, 290 (6%) had AHF. Sixty-two percent (n = 179) was diagnosed with HFpEF. Compared to HFrEF patients, HFpEF patients were more often women (48% vs. 31%, p = 0.004), less likely to have ischemic heart disease (31% vs. 53%, p = 0.002) and a pacemaker/ICD (7% vs. 21%, p < 0.001/1% vs. 8%, p < 0.001). Fewer HFpEF patients received intravenous diuretics (43% vs. 73%, p < 0.001) and inotropes (2% vs. 7%, p = 0.02), while more HFpEF patients received nitro-glycerine (59% vs. 44%, p = 0.02). Intubation/NIV, ICU admission, and revascularization were used similarly. Hospitalization was shorter for HFpEF patients (4 vs. 6 days, p < 0.001), with no significant difference in survival to discharge (96% vs. 91%, p = 0.07). Of AHF admissions, nearly two-thirds was due to HFpEF. Compared to HFrEF, HFpEF patients had a lower cardiac comorbidity and a 2-day shorter hospitalization.<br /> (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Subjects :
- Humans
Female
Male
Aged
Prospective Studies
Denmark epidemiology
Time Factors
Aged, 80 and over
Middle Aged
Treatment Outcome
Risk Factors
Hospital Mortality
Length of Stay
Risk Assessment
Registries
Heart Failure physiopathology
Heart Failure mortality
Heart Failure therapy
Heart Failure diagnosis
Stroke Volume
Ventricular Function, Left
Subjects
Details
- Language :
- English
- ISSN :
- 1937-5395
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of cardiovascular translational research
- Publication Type :
- Academic Journal
- Accession number :
- 37052785
- Full Text :
- https://doi.org/10.1007/s12265-023-10385-7