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T-cell lymphocytopenia: An omnipresent predictor of morbidity and mortality in consequence of SARS-CoV disease and influenza A infections.

Authors :
Putter JS
Seghatchian J
Source :
Cytokine [Cytokine] 2023 May; Vol. 165, pp. 156163. Date of Electronic Publication: 2023 Feb 16.
Publication Year :
2023

Abstract

Purpose of the Research: We proposed T-cell lymphocytopenia as a strategic predictor of serious coronavirus and influenza infections. Our preeminent goal was to determine whether a degree of T-cell lymphopenia would identify a distinct threshold cell count to differentiate between severe and non-severe infections. We codified an Index Severity Score to exploit an association between T-cell cytopenia and the grade of disease activity.<br />Principal Result: A T-cell count of 560 cells/uL or below signified a trend towards advanced disease.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1096-0023
Volume :
165
Database :
MEDLINE
Journal :
Cytokine
Publication Type :
Academic Journal
Accession number :
36989654
Full Text :
https://doi.org/10.1016/j.cyto.2023.156163