Treatment of Orofacial Granulomatosis-9-Month Follow-up: A Case Report.

Authors :: Sopi Krasniqi M
Sllamniku Dalipi Z
Kastrati Dragidella D
Kondirolli L
Source :: Clinical medicine insights. Case reports [Clin Med Insights Case Rep] 2023 Mar 14; Vol. 16, pp. 11795476231160046. Date of Electronic Publication: 2023 Mar 14 (Print Publication: 2023).
Publication Year :: 2023
Abstract: Orofacial granulomatosis is a condition that manifests clinically as painless labial enlargement, perioral and mucosal edema, oral ulcers, and gingivitis. It is characterized by non-necrotizing granulomatous inflammation of the oral and maxillofacial region. When the swelling only affects the lips, the pathology is called Miescher's granulomatous cheilitis; however, when it also causes facial paresis and lingua plicata, it is known as Melkersson-Rosenthal syndrome. We report a case that was successfully treated with a combination of a local (intralesional) steroid, a systemic antibiotic, and a systemic steroid. After 6 months of therapy, we observed improvement in gingival hyperplasia and buccal mucosa and lip edema.<br />Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.<br /> (© The Author(s) 2023.)