Back to Search
Start Over
Effect of dosage of orally administered 17α-methyltestosterone on sex reversion of the yellowtail tetra Astyanax lacustris (Lütken, 1875).
- Source :
-
Animal reproduction [Anim Reprod] 2023 Mar 06; Vol. 20 (1), pp. e20220080. Date of Electronic Publication: 2023 Mar 06 (Print Publication: 2023). - Publication Year :
- 2023
-
Abstract
- The females of yellowtail tetra ( Astyanax lacustris ), known as the freshwater sardine, are approximately 1.33 times larger than males, and thus, all-female monosex culture would increase production and reduce size variability. The present work aimed to identify the optimal dose of 17α-methyltestosterone (MT) to be used in the masculinization of A. lacustris for indirect sex reversal. Three different concentrations of MT (20, 40, and 60 mg/kg of feed in the diet) were fed to the fry for 30 days. Thirty adult individuals from each treatment, including the control (0 mg MT/kg), were evaluated for gonadal development, morphological and histological sexual identification, zootechnical performance, and the possible genotoxic effect caused by prolonged exposure to MT. MT significantly ( P <0.01) affected the differentiation of the gonads, with the presence of possible inhibitory effects in all treatments. Intersex individuals were present in the 20 and 60 mg MT/kg treatments. All treatments were able to masculinize A. lacustris and the treatment with the lowest hormone concentration produced the highest percentage of males 76.7%, while the control had 46.7% males. The presence of erythrocyte nuclear alterations indicated a possible cytotoxic effect of MT in treatments 40 and 60 mg MT/kg, however, the use of the hormone did not affect the growth and the survival of the individuals. Thus, the use of MT is a viable option for obtaining neomales as a first step into the production of all-female progenies.<br />Competing Interests: Conflicts of interest: The authors have no conflict of interest to declare.
Details
- Language :
- English
- ISSN :
- 1984-3143
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Animal reproduction
- Publication Type :
- Academic Journal
- Accession number :
- 36922988
- Full Text :
- https://doi.org/10.1590/1984-3143-AR2022-0080