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Hematopoietic cell transplants in resource-poor countries: challenges and opportunities.
- Source :
-
Expert review of hematology [Expert Rev Hematol] 2023 Mar; Vol. 16 (3), pp. 163-169. Date of Electronic Publication: 2023 Mar 21. - Publication Year :
- 2023
-
Abstract
- Introduction: Numbers of hematopoietic cell transplants continue to increase globally but most of this activity is in resource-rich countries. Limitations to increasing transplant activity in resource-poor countries include lack of sophisticated personnel and infrastructure, complexity in identifying and accessing donors, unavailability of some new drugs and high cost.<br />Areas Covered: We searched the biomedical literature for hematopoietic cell transplants and resource-rich and resource-poor countries. Recent advances which potentially make transplants more accessible in resource-poor countries include: (1) outpatient transplants; (2) grafts stored at 4°C; (3) less intensive pretransplant conditioning; (4) use of generic drugs; (5) less complex and costly donor access; and (6) increased collaboration with transplant centers in resource-rich countries.<br />Expert Opinion: We reviewed publications on the limitations and solutions discussed above. Paradoxically, most data we analyzed originate from resource-rich countries. We found no convincing epidemiological data to support a recent increased transplant rate in resource-poor countries yet but hope to see increases soon.
Details
- Language :
- English
- ISSN :
- 1747-4094
- Volume :
- 16
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Expert review of hematology
- Publication Type :
- Academic Journal
- Accession number :
- 36919565
- Full Text :
- https://doi.org/10.1080/17474086.2023.2191946