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[Dynamic distribution of methandrostenolone in the body of white rats].

Authors :
Krylov IuF
Krynetskiĭ EIu
Prokhorov BS
Sapozhnikova GA
Smirnov PA
Source :
Farmakologiia i toksikologiia [Farmakol Toksikol] 1987 Sep-Oct; Vol. 50 (5), pp. 48-51.
Publication Year :
1987

Abstract

Dynamics of distribution of anabolic steroidal hormone methandrostenolone and routes of its elimination from the organism of Wistar rats were studied by using methods of radioisotopes and high-performance liquid chromatography. Methandrostenolone metabolites were shown to be excreted mainly in the urine. Methandrostenolone metabolism is a complicated process in the course of which redistribution of metabolites among various organs occurs. The anabolic effect of methandrostenolone is supposed to be due to the formation of its metabolites.

Details

Language :
Russian
ISSN :
0014-8318
Volume :
50
Issue :
5
Database :
MEDLINE
Journal :
Farmakologiia i toksikologiia
Publication Type :
Academic Journal
Accession number :
3691778