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Unconventional and conventional Pickering emulsions: Perspectives and challenges in skin applications.

Authors :
Hazt B
Pereira Parchen G
Fernanda Martins do Amaral L
Rondon Gallina P
Martin S
Hess Gonçalves O
Alves de Freitas R
Source :
International journal of pharmaceutics [Int J Pharm] 2023 Apr 05; Vol. 636, pp. 122817. Date of Electronic Publication: 2023 Mar 09.
Publication Year :
2023

Abstract

Pickering emulsions are free from molecular and classical surfactants and are stabilized by solid particles, creating long-term stability against emulsion coalescence. Additionally, these emulsions are both environmentally and skin-friendly, creating new and unexplored sensorial perceptions. Although the literature mostly describes conventional emulsions (oil-in-water), there are unconventional emulsions (multiple, oil-in-oil and water-in-water) with excellent prospects and challenges in skin application as oil-free systems, permeation enhancers and topical drug delivery agents, with various possibilities in pharmaceutical and cosmetic products. However, up to now, these conventional and unconventional Pickering emulsions are not yet available as commercial products. This review brings to the discussion some important aspects such as the use of phases, particles, rheological and sensorial perception, as well as current trends in the development of these emulsions.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2023 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1873-3476
Volume :
636
Database :
MEDLINE
Journal :
International journal of pharmaceutics
Publication Type :
Academic Journal
Accession number :
36905974
Full Text :
https://doi.org/10.1016/j.ijpharm.2023.122817