A New Monoterpene Alkaloid from Incarvillea sinensis with Migration Inhibitory Activity on Cancer Cell.

Authors :: Song W
Zhang J
Zhao P
Huang Y
Zhang S
Source :: Chemistry & biodiversity [Chem Biodivers] 2023 Apr; Vol. 20 (4), pp. e202201203. Date of Electronic Publication: 2023 Mar 24.
Publication Year :: 2023
Abstract: A novel monoterpene alkaloid, named incarvine G, was isolated from the Incarvillea sinensis Lam. Its chemical structure was elucidated using comprehensive spectroscopic methods. Incarvine G is an ester compound comprised of a monoterpene alkaloid and glucose. This compound showed evident inhibition on cell migration, invasion, and cytoskeleton formation of human MDA-MB-231 with low cytotoxicity.<br /> (© 2023 Wiley-VHCA AG, Zurich, Switzerland.)

Subjects :: Humans
Alkaloids pharmacology
Alkaloids chemistry
Molecular Structure
Cell Migration Inhibition drug effects
Antineoplastic Agents chemistry
Antineoplastic Agents pharmacology
Bignoniaceae chemistry
Monoterpenes pharmacology
Monoterpenes chemistry

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