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Photoexcited cobalt catalysed endo -selective alkyl Heck reaction.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2023 Mar 28; Vol. 59 (26), pp. 3862-3865. Date of Electronic Publication: 2023 Mar 28. - Publication Year :
- 2023
-
Abstract
- Herein, we report an intramolecular endo -selective Heck reaction of iodomethylsilyl ethers of phenols and alkenols. The reaction leads to the formation of seven- and eight-membered siloxycycles in excellent yields, which could be further converted into the corresponding allylic alcohols upon oxidation. Thus, this method could be used for the selective ( Z )-hydroxymethylation of o -hydroxystyrenes and alkenols. Rapid scan EPR experiments and DFT calculations suggest a concerted β -hydrogen elimination event to take place in the triplet state.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 59
- Issue :
- 26
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 36883973
- Full Text :
- https://doi.org/10.1039/d2cc06967a