Back to Search Start Over

Seven new pentasaccharides from the roots of Rehmannia glutinosa .

Authors :
Liu YF
Zhou J
Zhang WQ
Shi GR
Li XY
Sun MH
Zhao YP
Chen RY
Yu DQ
Source :
Journal of Asian natural products research [J Asian Nat Prod Res] 2024 Feb; Vol. 26 (2), pp. 280-292. Date of Electronic Publication: 2023 Mar 06.
Publication Year :
2024

Abstract

Seven new pentasaccharides ( 1 - 7 ), rehmaglupentasaccharides A-G, were isolated from the air-dried roots of Rehmannia glutinosa . Their structures were established from the spectroscopic data obtained and by chemical evidence. The known verbascose ( 8 ) and stachyose ( 9 ) were also obtained in the current investigation, and the structure of stachyose was unequivocally defined using X-ray diffraction data. Compounds 1 - 9 were tested for their cytotoxicity against five human tumor cell lines, influence on dopamine receptor activation, and proliferation effects against Lactobacillus reuteri .

Details

Language :
English
ISSN :
1477-2213
Volume :
26
Issue :
2
Database :
MEDLINE
Journal :
Journal of Asian natural products research
Publication Type :
Academic Journal
Accession number :
36877100
Full Text :
https://doi.org/10.1080/10286020.2023.2184356