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[A Case of m0CRPC after Hormone Therapy for Pelvic Lymph Node Metastasis in which Salvage RARP was Effective].

Authors :
Kokubun H
Kubota M
Kambe T
Mine Y
Hagimoto H
Yamaguchi R
Murata S
Makita N
Hattori Y
Abe Y
Tsutsumi N
Yamasaki T
Inoue K
Kawakita M
Source :
Hinyokika kiyo. Acta urologica Japonica [Hinyokika Kiyo] 2023 Feb; Vol. 69 (2), pp. 59-62.
Publication Year :
2023

Abstract

The patient was a 63-year-old man with biopsy Gleason score of 4+5 prostate cancer with an initial prostate specific antigen level of (PSA) 51.2ng/ml. On imaging examination, extracapsular invasion, rectal invasion, and pararectal lymph node metastasis were found (cT4N1M0). After 4 years of androgen deprivation therapy, PSA decreased to 0.631ng/ml, and then increased gradually to1.2ng/ml. Computed tomographic scan showed that the primary tumor had shrunk and lymph node metastasis had disappeared; so salvage robot-assisted resection of the prostate (RARP) was performed for non-metastatic castration-resistant prostate cancer (m0CRPC). Since PSA decreased to an undetactable level, hormone therapy was terminated at 1 year. The patient remained recurrence-free for 3 years after surgery. RARP may be effective for m0CRPC, enabling discontinuation of androgen deprivation therapy.

Details

Language :
Japanese
ISSN :
0018-1994
Volume :
69
Issue :
2
Database :
MEDLINE
Journal :
Hinyokika kiyo. Acta urologica Japonica
Publication Type :
Academic Journal
Accession number :
36863873
Full Text :
https://doi.org/10.14989/ActaUrolJap_69_2_59