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Unilateral perirolandic polymicrogyria with ipsilateral brainstem hypoplasia and compensatory contralateral hyperplasia.
- Source :
-
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2023 Jul; Vol. 44 (7), pp. 2617-2619. Date of Electronic Publication: 2023 Mar 02. - Publication Year :
- 2023
-
Abstract
- Polymicrogyria (PMG) is a malformation of cortical development that occurs mostly in the perisylvian region bilaterally (60-70%), most often presenting with epilepsy. Unilateral cases are much rarer with hemiparesis being the predominant symptom. We report a case of a 71-year-old man with right perirolandic PMG with ipsilateral hypoplasia and contralateral hyperplasia of the brainstem, with only non-progressive left-sided mild spastic hemiparesis. This imaging pattern is thought to occur due to the normal process of withdrawal of the axons of the corticospinal tract (CST) connected to aberrant cortex, possibly with compensatory contralateral CST hyperplasia. However, the majority of cases is additionally present with epilepsy. We believe it is worthwhile to investigate imaging patterns of PMG with symptoms' correlation, particularly with the help of techniques such as advanced brain imaging to assist in the study of cortical development along with adaptive somatotopic organization of the cerebral cortex in MCD with possible clinical applications.<br /> (© 2023. Fondazione Società Italiana di Neurologia.)
- Subjects :
- Male
Humans
Aged
Hyperplasia complications
Hyperplasia diagnostic imaging
Hyperplasia pathology
Cerebral Cortex pathology
Brain Stem diagnostic imaging
Paresis
Magnetic Resonance Imaging
Polymicrogyria complications
Polymicrogyria diagnostic imaging
Polymicrogyria pathology
Epilepsy pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1590-3478
- Volume :
- 44
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 36862200
- Full Text :
- https://doi.org/10.1007/s10072-023-06657-4