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Enhancer Coamplification and Hijacking Promote Oncogene Expression in Liposarcoma.

Authors :
Liu T
Wang J
Yang H
Jin Q
Wang X
Fu Y
Luan Y
Wang Q
Youngblood MW
Lu X
Casadei L
Pollock R
Yue F
Source :
Cancer research [Cancer Res] 2023 May 02; Vol. 83 (9), pp. 1517-1530.
Publication Year :
2023

Abstract

Significance: Comprehensive profiling of the enhancer landscape and 3D genome structure in liposarcoma identifies extensive enhancer-oncogene coamplification and enhancer hijacking events, deepening the understanding of how oncogenes are regulated in cancer.<br /> (©2023 The Authors; Published by the American Association for Cancer Research.)

Details

Language :
English
ISSN :
1538-7445
Volume :
83
Issue :
9
Database :
MEDLINE
Journal :
Cancer research
Publication Type :
Academic Journal
Accession number :
36847778
Full Text :
https://doi.org/10.1158/0008-5472.CAN-22-1858