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Wood dust and asthma.
- Source :
-
Current opinion in allergy and clinical immunology [Curr Opin Allergy Clin Immunol] 2023 Apr 01; Vol. 23 (2), pp. 76-84. Date of Electronic Publication: 2023 Feb 06. - Publication Year :
- 2023
-
Abstract
- Purpose of the Review: Review recent developments on asthma associated with wood dust, given the increasing scale of wood handling and processing activities globally.<br />Recent Findings: Work in wood industries is associated with a significantly increased risk of respiratory symptoms, rhinitis and asthma. This can be attributed to traditional processing techniques and newer technologies producing complex bioaerosol exposures, which may include chemicals. Meta-analysis studies indicate strong evidence for wood dusts as occupational sensitizers for asthma, but the underlying mechanisms remain poorly understood. The global prevalence of asthma in wood workers ranges between 6-18% and for rhinitis 16-33%. Exposure estimates show wide variation. Risk factors include atopy and exposure to certain wood species, elevated current and cumulative particulate exposures.<br />Summary: Future studies should focus on better characterization of wood dust allergens and other bioaerosol components, specific immunoglobulin E responses to different wood species, pathophysiological mechanisms underlying asthma, and modelling dose-response relationships using refined exposure metrics for dust particulate and other bioaerosol components. There is a need for improved health-based international exposure standards and effective workplace control measures to reduce exposures to wood dust particulate (hard and soft woods), endotoxin and β-glucan, to reduce the risks of asthma in wood workers.<br /> (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1473-6322
- Volume :
- 23
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Current opinion in allergy and clinical immunology
- Publication Type :
- Academic Journal
- Accession number :
- 36821481
- Full Text :
- https://doi.org/10.1097/ACI.0000000000000882