Biological Restraint on the Izhikevich Neuron Model Essential for Seizure Modeling.

We propose a simple modification of the Izhikevich neuron model to restrict firing rates of neurons. We demonstrate how this modification affects overall network activity using a simple artificial network. Such restraint on the Izhikevich neuron model would be especially important in larger scale simulations or when frequency dependent short-term plasticity is one of the network components. Although maximum firing rates are most likely exceeded in simulations of seizure like activity or other conditions that promote excessive excitation, we show that restriction of neuronal firing frequencies has impact even on small networks with moderate levels of input.