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Medication-related osteonecrosis of the upper jaw involving the zygomatic bone: A case report.
- Source :
-
International journal of surgery case reports [Int J Surg Case Rep] 2023 Mar; Vol. 104, pp. 107932. Date of Electronic Publication: 2023 Feb 17. - Publication Year :
- 2023
-
Abstract
- Introduction and Importance: Osteonecrosis of the jaw resulting from treatment with antiresorptive agents, such as bisphosphonates and denosumab, is widely recognized as medication-related osteonecrosis of the jaw (MRONJ). However, to the best of our knowledge, there are no reports of medication-related osteonecrosis of the upper jaw extending to the zygomatic bone.<br />Case Presentation: An 81-year-old woman treated with denosumab for multiple lung cancer bone metastases presented to the authors' hospital with a swelling in the upper jaw. Computed tomography showed osteolysis, periosteal reaction of the maxillary bone, maxillary sinusitis, and osteosclerosis of the zygomatic bone. The patient underwent conservative treatment; however, osteosclerosis of the zygomatic bone progressed to osteolysis.<br />Clinical Discussion: If the maxillary MRONJ extends to the surrounding bony structures, such as the orbit and skull base, serious complications may occur.<br />Conclusion: It is important to detect early signs of maxillary MRONJ, before it involves the surrounding bones.<br />Competing Interests: Declaration of competing interest None.<br /> (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 2210-2612
- Volume :
- 104
- Database :
- MEDLINE
- Journal :
- International journal of surgery case reports
- Publication Type :
- Report
- Accession number :
- 36801766
- Full Text :
- https://doi.org/10.1016/j.ijscr.2023.107932