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Congenital syphilis: a rare presentation of a forgotten infection.

Authors :
Hegde A
Srinivasan R
Dinakar C
Source :
Journal of infection in developing countries [J Infect Dev Ctries] 2023 Jan 31; Vol. 17 (1), pp. 135-138. Date of Electronic Publication: 2023 Jan 31.
Publication Year :
2023

Abstract

Congenital syphilis (CS), a common but forgotten disease has a broad spectrum of clinical presentation. Vertical transmission of this spirochaetal infection from the pregnant mother to the foetus can result in varied manifestations ranging from asymptomatic infection to life- threatening conditions in the form of stillbirth and neonatal death. The haematological and visceral manifestations of this disease can closely mimic various conditions including haemolytic anaemia and malignancies. Congenital syphilis should be considered as a differential in any infant presenting with hepatosplenomegaly and haematological abnormalities even if the antenatal screen was negative. We report a 6-month-old infant with congenital syphilis presenting with organomegaly, bicytopenia and monocytosis. A strong index of suspicion and early diagnosis is the key to the good outcome as treatment is simple and cost- effective.<br />Competing Interests: No Conflict of Interest is declared<br /> (Copyright (c) 2023 Anusha Hegde, Ranjini Srinivasan, Chitra Dinakar.)

Details

Language :
English
ISSN :
1972-2680
Volume :
17
Issue :
1
Database :
MEDLINE
Journal :
Journal of infection in developing countries
Publication Type :
Academic Journal
Accession number :
36795921
Full Text :
https://doi.org/10.3855/jidc.15498