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The use of sealing hemostat patch (HEMOPATCH ® ) in laparotomic myomectomy: a prospective case-control study.

Authors :
Montera R
Ficarola F
Plotti F
Terranova C
De Cicco Nardone C
Guzzo F
Angioli R
Luvero D
Source :
Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2023 May; Vol. 307 (5), pp. 1521-1528. Date of Electronic Publication: 2023 Feb 15.
Publication Year :
2023

Abstract

Purpose: Uterine myomas are the most common gynecological disease. In these cases, a myomectomy is performed traditionally laparotomically. However, alternatives have been widely used, including laparoscopic, endoscopic, and robotic surgery. During these techniques, diffuse parenchymatous bleeding remains one of the main intraoperative and postoperative complications and sometimes requires unplanned hysterectomies. Recently, hemostatic agents and sealants have been used to prevent excessive blood loss during surgical repair.<br />Methods: We propose a prospective case-control study on the use of a sealing hemostat patch (HEMOPATCH <superscript>®</superscript> ) on uterine sutures in laparotomic myomectomy. In the period between July 2016 and April 2017, 46 patients with symptomatic uterine fibromatosis underwent surgery. They were divided into two groups of 23 patients, with different treatments in the hemostatic phase of oozing bleeding. HEMOPATCH <superscript>®</superscript> is applied in group A, and spray electrocoagulation is applied in group B.<br />Results: In group A, we achieve faster hemostasis (p < 0.05), than in group B. We report a significantly lower C-reactive protein value on the second and third days after surgery for group A compared to group B.<br />Conclusions: HEMOPATCH <superscript>®</superscript> , during laparotomic myomectomy, is a valid alternative solution for obtaining rapid hemostasis and consequently intraoperative and postoperative bleeding. Furthermore, we suggest that a lower inflammatory peritoneal state is probably correlated with the barrier effect of the patch on the suture.<br /> (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Details

Language :
English
ISSN :
1432-0711
Volume :
307
Issue :
5
Database :
MEDLINE
Journal :
Archives of gynecology and obstetrics
Publication Type :
Academic Journal
Accession number :
36790464
Full Text :
https://doi.org/10.1007/s00404-023-06957-2