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Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement.

Authors :
Mangione CM
Barry MJ
Nicholson WK
Cabana M
Chelmow D
Coker TR
Davis EM
Donahue KE
Jaén CR
Kubik M
Li L
Ogedegbe G
Pbert L
Ruiz JM
Stevermer J
Wong JB
Source :
JAMA [JAMA] 2023 Feb 14; Vol. 329 (6), pp. 502-507.
Publication Year :
2023

Abstract

Importance: Genital herpes is a common sexually transmitted infection caused by 2 related viruses, herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Infection is lifelong; currently, there is no cure for HSV infection. Antiviral medications may provide clinical benefits to symptomatic persons. Transmission of HSV from a pregnant person to their infant can occur, most commonly during delivery; when genital lesions or prodromal symptoms are present, cesarean delivery can reduce the risk of transmission. Neonatal herpes infection is uncommon yet can result in substantial morbidity and mortality.<br />Objective: To reaffirm its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update on targeted key questions to systematically evaluate the evidence on accuracy, benefits, and harms of routine serologic screening for HSV-2 infection in asymptomatic adolescents, adults, and pregnant persons.<br />Population: Adolescents and adults, including pregnant persons, without known history, signs, or symptoms of genital HSV infection.<br />Evidence Assessment: The USPSTF concludes with moderate certainty that the harms outweigh the benefits for population-based screening for genital HSV infection in asymptomatic adolescents and adults, including pregnant persons.<br />Recommendation: The USPSTF recommends against routine serologic screening for genital HSV infection in asymptomatic adolescents and adults, including pregnant persons. (D recommendation).

Details

Language :
English
ISSN :
1538-3598
Volume :
329
Issue :
6
Database :
MEDLINE
Journal :
JAMA
Publication Type :
Academic Journal
Accession number :
36786784
Full Text :
https://doi.org/10.1001/jama.2023.0057