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Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement.
- Source :
-
JAMA [JAMA] 2023 Feb 14; Vol. 329 (6), pp. 502-507. - Publication Year :
- 2023
-
Abstract
- Importance: Genital herpes is a common sexually transmitted infection caused by 2 related viruses, herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Infection is lifelong; currently, there is no cure for HSV infection. Antiviral medications may provide clinical benefits to symptomatic persons. Transmission of HSV from a pregnant person to their infant can occur, most commonly during delivery; when genital lesions or prodromal symptoms are present, cesarean delivery can reduce the risk of transmission. Neonatal herpes infection is uncommon yet can result in substantial morbidity and mortality.<br />Objective: To reaffirm its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update on targeted key questions to systematically evaluate the evidence on accuracy, benefits, and harms of routine serologic screening for HSV-2 infection in asymptomatic adolescents, adults, and pregnant persons.<br />Population: Adolescents and adults, including pregnant persons, without known history, signs, or symptoms of genital HSV infection.<br />Evidence Assessment: The USPSTF concludes with moderate certainty that the harms outweigh the benefits for population-based screening for genital HSV infection in asymptomatic adolescents and adults, including pregnant persons.<br />Recommendation: The USPSTF recommends against routine serologic screening for genital HSV infection in asymptomatic adolescents and adults, including pregnant persons. (D recommendation).
- Subjects :
- Adolescent
Adult
Female
Humans
Infant, Newborn
Pregnancy
Herpes Simplex diagnosis
Herpes Genitalis diagnosis
Herpes Genitalis drug therapy
Herpesvirus 1, Human
Herpesvirus 2, Human
Mass Screening adverse effects
Mass Screening psychology
Pregnancy Complications, Infectious diagnosis
Pregnancy Complications, Infectious drug therapy
Pregnancy Complications, Infectious prevention & control
Serologic Tests adverse effects
Serologic Tests methods
Serologic Tests psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1538-3598
- Volume :
- 329
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- JAMA
- Publication Type :
- Academic Journal
- Accession number :
- 36786784
- Full Text :
- https://doi.org/10.1001/jama.2023.0057