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FIRE Mimics a 14-3-3-Binding Motif to Promote Phytophthora palmivora Infection.
- Source :
-
Molecular plant-microbe interactions : MPMI [Mol Plant Microbe Interact] 2023 Jun; Vol. 36 (6), pp. 315-322. Date of Electronic Publication: 2023 Jul 27. - Publication Year :
- 2023
-
Abstract
- The oomycete Phytophthora palmivora infects a wide range of tropical crops worldwide. Like other filamentous plant pathogens, it secretes effectors to colonize plant tissues. Here, we characterize FIRE, an RXLR effector that contains a canonical mode I 14-3-3 phospho-sensor-binding motif that is conserved in effectors of several Phytophthora species. FIRE is phosphorylated in planta and interacts with multiple 14-3-3 proteins. Binding is sensitive to the R18 14-3-3 inhibitor. FIRE promotes plant susceptibility and co-localizes with its target around haustoria. This work uncovers a new type of oomycete effector target mechanism. It demonstrates that substrate mimicry for 14-3-3 proteins is a cross-kingdom effector strategy used by both prokaryotic and eukaryotic plant pathogens to suppress host immunity. [Formula: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY 4.0 International license.<br />Competing Interests: The author(s) declare no conflict of interest.
- Subjects :
- 14-3-3 Proteins
Plants
Plant Diseases
Phytophthora
Subjects
Details
- Language :
- English
- ISSN :
- 0894-0282
- Volume :
- 36
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Molecular plant-microbe interactions : MPMI
- Publication Type :
- Academic Journal
- Accession number :
- 36734982
- Full Text :
- https://doi.org/10.1094/MPMI-12-22-0251-R