Modification of bimetal Zn/ Mg MOF with nanoparticles Fe 3 O 4 and Fe 3 O 4 @SiO 2 , investigation of the peroxidase-like activity of these compounds by calorimetry and fluorimetry methods.

In this article; the bimetal metal-organic framework Zn/Mg (Zn/Mg MOF) is synthesized. Then Zn/Mg MOF bimetal was combined with Fe ₃ O ₄ and Fe ₃ O ₄ @SiO ₂ , and composites of Fe ₃ O ₄ @ SiO ₂ /MOF/Dextrin, Fe ₃ O ₄ @SiO ₂ /MOF, Fe ₃ O ₄ @MOF/Dextrin and Fe ₃ O ₄ @MOF made. The peroxidase-like activity of these compounds was investigated and compared by calorimetric Resazurin (Rz) and O-phenylenediamine (OPD); (Rz-H ₂ O ₂ , OPD-H ₂ O ₂ ) and fluorimetric Rz and terephtalic acid (TA); (Rz-H ₂ O ₂ , TA-H ₂ O ₂ ). The Fe ₃ O ₄ @ MOF/Dextrin composite has the highest peroxidase-like activity. The effect factors (amount of pH (6), the values of TA (1.37 mM), H ₂ O ₂ (0.025 mM), reaction time (8.15 min), and amount of Composite (116.67 mg)) to increase the catalytic activity of Fe ₃ O ₄ @ MOF/Dextrin measured by chemometrics method. The most suitable linear range of the calibration curve by the TA-H ₂ O ₂ -Composite fluorimetric method is 1-600 μg L ^-1 , and the detection limit is 2.27 μg L ^-1 . The relative standard deviation (RSD%) for measuring concentration atropine 1 μg L ^-1 (n = 6) is 1.18%. Finally, from this system for measuring atropine extracted by the Liquid-liquid extraction (LLE) method in two types of plants, D. Innoxia north and west and D. stramonium north and west of Iran (118.25 μg L ^-1 , 79.80 μg L ^-1 ) and (18.477 μg L ^-1 , 9.27 μg L ^-1 ) used, respectively.
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