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Horner syndrome as a physiological biomarker of disease in canine cervical myelopathy.
- Source :
-
Journal of veterinary internal medicine [J Vet Intern Med] 2023 Mar; Vol. 37 (2), pp. 598-605. Date of Electronic Publication: 2023 Jan 26. - Publication Year :
- 2023
-
Abstract
- Background: Horner syndrome often occurs with cervical myelopathies and might provide insight into the underlying disease and prognosis.<br />Objectives: To describe the clinical and imaging features of dogs with cervical myelopathy and concurrent Horner syndrome and to determine association of Horner syndrome with diseases or magnetic resonance images (MRI).<br />Animals: Ninety-three client-owned dogs with cervical myelopathy and concurrent Horner syndrome and 99 randomly selected client-owned dogs with cervical myelopathy without Horner syndrome (control cases).<br />Methods: Retrospective study. Medical records were reviewed to identify Horner and control cases and clinical findings recorded. MRI were reviewed, and lesions characterized and recorded. Descriptive and comparative statistics were performed.<br />Results: Non-compressive disease occurred more frequently in the Horner group compared with controls (58%; 95% CI: 48-68 vs 9%; 95% CI: 5-16; Pā<ā.0001). The most common diseases were fibrocartilaginous embolism in the Horner group (44/93; 47%) and intervertebral disc extrusion (76/99; 77%) amongst controls. On MRI, parenchymal hyperintensity was seen more commonly in the Horner group (95%; 95% CI: 88-98) compared with controls (51%; 95% CI: 41-60; Pā<ā.0001). In the Horner group, dogs that did not survive to discharge (N = 13) had more extensive MRI lesions relative to the adjacent vertebral length (200%; IQR 110%-575%) compared with survivors (N = 80; 110%; IQR 40%-250%; P = .02). Lateralization of Horner signs and MRI changes matched in 54% of cases. The overall survival rate was high in both Horner (80/93; 86%) and control (95/99; 96%) groups.<br />Conclusions and Clinical Importance: Horner syndrome in cervical myelopathy is commonly associated with noncompressive intraparenchymal disease.<br /> (© 2023 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.)
Details
- Language :
- English
- ISSN :
- 1939-1676
- Volume :
- 37
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of veterinary internal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 36704850
- Full Text :
- https://doi.org/10.1111/jvim.16588