Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022.

Authors :: Berens-Riha N
De Block T
Rutgers J
Michiels J
Van Gestel L
Hens M
Kenyon C
Bottieau E
Soentjens P
van Griensven J
Brosius I
Ariën KK
Van Esbroeck M
Rezende AM
Vercauteren K
Liesenborghs L
Source :: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2022 Dec; Vol. 27 (48).
Publication Year :: 2022
Abstract: Vaccination is important in containing the 2022 mpox (formerly monkeypox) epidemic. We describe five Belgian patients with localised severe symptoms of proctitis and penile oedema, occurring between 4 and 35 days after post-exposure preventive vaccination or after one- or two-dose off-label pre-exposure preventive vaccination with MVA-BN vaccine. Genome sequencing did not reveal evidence for immune escape variants. Healthcare workers and those at risk should be aware of possible infections occurring shortly after vaccination and the need for other preventive measures.

Subjects :: Humans
Belgium epidemiology
Vaccination adverse effects
Mpox (monkeypox) prevention & control
Smallpox Vaccine adverse effects

Language :: English
ISSN :: 1560-7917
Volume :: 27
Issue :: 48
Database :: MEDLINE
Journal :: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Publication Type :: Academic Journal
Accession number :: 36695462
Full Text :: https://doi.org/10.2807/1560-7917.ES.2022.27.48.2200894

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